Fig. 1
From: Metagenomic cross-talk: the regulatory interplay between immunogenomics and the microbiome
Effects of the microbiota on host gene regulation. Examples of epigenetic and transcriptional changes induced by commensal colonization in the intestine. Arrows denote bacterial signals involved in the genetic reprogramming of immune cell subsets and intestinal epithelial cells. Question marks indicate unknown microbial signals involved in the regulation of gene expression in macrophages, innate lymphoid cells, and intestinal epithelial cells. T h 17 T helper 17