Fig. 1From: Signatures of early frailty in the gut microbiotaOTU abundances significantly different between twin pairs discordant for frailty. Pairwise plots of abundance between twin pairs discordant for frailty are shown for OTUs that were significant at P <0.05 after Bonferonni adjustment considering both MZ and DZ pairs. Paired Wilcoxon rank-signed tests were used to compare abundances for the 22 significantly associated OTUs associated with FI after alpha adjustment. Three were significantly different; the Dorea OTU was significantly increased in frailer twins (P <10−4), whilst the F. prausnitzii and Lachnospiraceae OTUs were significantly lower (P = 0.001 and P <10−3, respectively). Note there are overlapping data points where multiple twins had zero counts (log abundance −6) for OTUsBack to article page