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Fig. 1 | Genome Medicine

Fig. 1

From: Signatures of early frailty in the gut microbiota

Fig. 1

OTU abundances significantly different between twin pairs discordant for frailty. Pairwise plots of abundance between twin pairs discordant for frailty are shown for OTUs that were significant at P <0.05 after Bonferonni adjustment considering both MZ and DZ pairs. Paired Wilcoxon rank-signed tests were used to compare abundances for the 22 significantly associated OTUs associated with FI after alpha adjustment. Three were significantly different; the Dorea OTU was significantly increased in frailer twins (P <10−4), whilst the F. prausnitzii and Lachnospiraceae OTUs were significantly lower (P = 0.001 and P <10−3, respectively). Note there are overlapping data points where multiple twins had zero counts (log abundance −6) for OTUs

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