Fig. 5
Characteristics of inter-tissue unidirectional relationships. a Gene types of source nodes in the top ten most significant gene-to-module relationships in each tissue pair. Protein coding genes were enriched among source nodes (p value = 1.6 × 10−21). b Numbers of unique GOBPs that are inter-tissue regulated in a unidirectional way. For each source node we therefore picked only the top significantly enriched GOBP associated with its gene cluster (listed in Additional file 7). The most biologically diverse interactions are from thyroid to artery. lincRNA long intergenic non-coding RNA