Fig. 2

Taxonomic and functional profiles of twin gut microbiomes accompanied by T2D/obesity clinical indicators. a Clustered taxonomic profiles, discretized and with groups of tightly covarying taxa binned into 15 clusters for visualization. Each row represents a cluster of one or more species, and each column is one sample colored by the twin variable. Values indicate relative abundances from the medoid member of each cluster (see Additional file 5: Figure S3 for full matrix). b As (a) for metabolic modules derived from metagenomic functional profiling. Sample clustering retains ordering from (a). c Corresponding clustering of selected discretized clinical biomarkers, again retaining ordering from (a)