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Table 6 Reclassification when sample size doubled

From: Reclassification of genetic-based risk predictions as GWAS data accumulate

  

Future SNPs

Future SNPs

  

BrCa

CHD

Current SNPS

Risk

Low

Average

High

Low

Average

High

Low

0.074

0.026

0.000

0.016

0.007

0

Average

0.265

0.508

0.083

0.076

0.857

0.033

High

0.001

0.021

0.021

0.000

0.004

0.006

  

T2D

PrCa

Current SNPS

Risk

Low

Average

High

Low

Average

High

Low

0.120

0.037

0

0.040

0.016

0.000

Average

0.182

0.535

0.065

0.178

0.676

0.066

High

0.000

0.027

0.034

0.000

0.012

0.012

  1. Entries are the proportion of individuals who are classified as Lower Risk (<0.5× average), Average Risk (between <0.5× average and >2× average), or Higher Risk (>2× average) risk based on: (1) currently known risk SNPs (rows) and (2) the risk SNPs known after a hypothetical future GWAS that doubles the size of the largest current GWAS (columns)