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Table 6 Reclassification when sample size doubled

From: Reclassification of genetic-based risk predictions as GWAS data accumulate

   Future SNPs Future SNPs
   BrCa CHD
Current SNPS Risk Low Average High Low Average High
Low 0.074 0.026 0.000 0.016 0.007 0
Average 0.265 0.508 0.083 0.076 0.857 0.033
High 0.001 0.021 0.021 0.000 0.004 0.006
   T2D PrCa
Current SNPS Risk Low Average High Low Average High
Low 0.120 0.037 0 0.040 0.016 0.000
Average 0.182 0.535 0.065 0.178 0.676 0.066
High 0.000 0.027 0.034 0.000 0.012 0.012
  1. Entries are the proportion of individuals who are classified as Lower Risk (<0.5× average), Average Risk (between <0.5× average and >2× average), or Higher Risk (>2× average) risk based on: (1) currently known risk SNPs (rows) and (2) the risk SNPs known after a hypothetical future GWAS that doubles the size of the largest current GWAS (columns)