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Table 2 Enrichment analysis of genes with SNV and IS events. Significant enrichment in classes and pathways assessed using hypergeometric distribution test based on abundance of genes in each category in ACICU, integrated with PanOCT shared clusters report (see text for detail)

From: Genome dynamics of multidrug-resistant Acinetobacter baumannii during infection and treatment

  SNVs ISAba1
  Number of genes in ACICU Isolate-specific Patient-restricted Patient-specific Isolate-specific Patient-restricted Patient-specific
Transporters 282 30*** 4 23* 3 0 2
Transcription factors 207 5 2 20** 2 0 4*
Two component regulatory system 26 19*** 5*** 11*** 2 0 4
Lipid A and capsular polysaccharide synthesis 54 7** 2* 5 1 0 0
Iron transport 64 8** 1 4 0 0 1
Motility 31 4* 1 3 1 1 1
Total non-synonymous and non-neutral events used in hypergeometric test calculations   123 28 215 21 2 18
  1. * <0.05, ** <0.005, *** <0.0005