Fig. 2

STAT enhances weight gain and adiposity. a Scale weight was measured 3–5 times each week beginning at week 4 (day 28) of life. Group data were smoothed to the second order (3-neighbor method). p values were calculated using piecewise linear regression to assess rate of growth. b, c Weight at week 4 (b) and sacrifice (week 32; c). p values reflect ANOVA with Bonferroni’s correction for multiple comparisons. A high-fat diet (45 % kcal from fat) was introduced to all groups at week 13. DEXA was used at 4, 8, 12, 20, 24, and 28 weeks of life and values are shown as Mean ± SD. d, e Lean mass in male and female mice. f, g Fat mass in male and female mice. Data in a, d, e, f, and g are reported as mean ± SEM. p values calculated from individual mouse data (Mann–Whitney U test). In all panels: *p <0.05; ***p <0.001