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Fig. 2 | Genome Medicine

Fig. 2

From: An adaptive association test for microbiome data

Fig. 2

Type I error and power comparison for scenario 1 with a binary outcome. A selected phylogenetic cluster (6.7 %) of the OTUs was associated with the outcome. a X and Z are independent and b X and Z are correlated. K u, K w, and K 5 represent MiRKAT results from the unweighted UniFrac kernel, weighted UniFrac kernel, and generalized UniFrac kernel with α=0.5, respectively. K opt represents the simulation results for optimal MiRKAT considering the Bray–Curtis kernel, unweighted UniFrac kernel, weighted UniFrac kernel, and generalized UniFrac kernel. MiSPUw(2), MiSPUw(), and aMiSPUw represent the MiSPUw test with γ=2, and aMiSPUw summarizing γ=2,3,…,8,, respectively. aMiSPUu and aMiSPU represent the test summarizing γ=2,3,…,8, with unweighted generalized taxon proportion and combining aMiSPUu and aMiSPUw, respectively. KW represents Kruskal-Wallis test. Results were presented at n=100. KW Kruskal–Wallis test

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