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Fig. 4 | Genome Medicine

Fig. 4

From: Epigenetic changes mediated by polycomb repressive complex 2 and E2a are associated with drug resistance in a mouse model of lymphoma

Fig. 4

H3K27me3 ChIP-seq analysis. a Clusters of promoters based on their H3K27me3 levels in the parental and resistant lines (n = 2). TSS transcription start site. b Group K1 shows enrichment for developmental genes. GO gene ontology. c Group K2 shows enrichment for cell cycle-regulated genes. d Average H2K27me3 levels across E2a-bound genes. e Analysis of E2a-bound genes in the three clusters

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