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Table 1 Demographics of patient sub-cohort for whom genomics data were successfully generated

From: Development and clinical application of an integrative genomic approach to personalized cancer therapy

Characteristics Number (%) of patients (N = 46)
Age at diagnosisa (median and range, years) 48 (12–69)
Gender
 Women 26 (56.5 %)
 Men 20 (43.5 %)
Raceb
 White 18 (39.1 %)
 Unknown 16 (34.8 %)
 Other 5 (10.9 %)
 Asian 3 (6.5 %)
 Black or African American 3 (6.5 %)
 American Indian or Alaska Native 1 (2.2 %)
 Native Hawaiian or Other Pacific Islander 0 (0.0 %)
Cancer type
 Colorectalc 18 (39.1 %)
 Other (single-primary)d 7 (15.2 %)
 Breastc 6 (13.0 %)
 Multiple primariese 6 (13.0 %)
 Medullary thyroid carcinoma 5 (10.9 %)
 Unknown primary 4 (8.7 %)
Had metastatic disease at diagnosisa
 Yes 21 (45.7 %)
 No 23 (50.0 %)
 Unknown 2 (4.3 %)
Had metastatic disease at time of collection of sequenced tumor specimen
 Yes 28 (60.9 %)
 No 16 (34.8 %)
 Unknown 2 (4.3 %)
Sequenced tumor specimen type
 Primary 22 (47.8 %)
 Metastatic 13 (28.2 %)
 Unknown 4 (8.7 %)
 Primary and metastatic 3 (6.5 %)
 Lymph node 2 (4.3 %)
 Primary and lymph node 1 (2.2 %)
 Local recurrence 1 (2.2 %)
Patient type
 Internal (have cancer care in Mount Sinai EMR) 22 (47.8 %)
 External 24 (52.2 %)
  1. aFor patients with multiple primaries (N = 6), the indicated characteristic is given for disease corresponding to the most recent primary
  2. bEthnicity information (Hispanic/Latino or non-Hispanic/Latino) was not collected
  3. cThe number represents patients with the indicated tumor type exclusively. Patients with multiple primaries including the indicated tumor type are not counted here, but counted in the “multiple primaries” category. One patient had two breast cancer tumors during her lifetime that were classified as independent primaries, therefore her count is given under “breast” as cancer type, although she counts as “multiple primaries” in tabulating other characteristics
  4. dOther single-primary cancer types (N = 1 for each) are: carcinoid tumor of the midgut, glial neoplasia, malignant insulinoma, leiomyosarcoma, malignant peripheral nerve sheath tumor, pancreatic cancer, and squamous cell carcinoma of the tongue
  5. ePatients with multiple primaries had these combinations: breast and non-small-cell lung cancer; breast and colon cancer; breast and follicular papillary thyroid cancer; leukemia and squamous cell carcinoma of the skin; ovarian, lung, and thyroid cancer; sarcoma and non-small-cell lung cancer