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Fig. 2 | Genome Medicine

Fig. 2

From: The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p

Fig. 2

Conserved miRNA expression in mouse in vitro and in vivo differentiated and alternatively activated macrophages. a Stem-loop RT-qPCR-based measurement of miR-342-3p, miR-193b, miR-99b, and miR-125a-5p expression in IL-4-stimulated and unstimulated mouse bone marrow-derived macrophages. Each data point represents the mean and standard deviation of three individual animals. *P ˂ 0.05, **P ˂ 0.01; ns. not significant. b Stem-loop RT-qPCR-based quantification of miR-342-3p, miR-99b, and miR-125a-5p in mouse thioglycolate-elicited and in vivo alternatively activated macrophages. Each data point represents the mean and standard deviation of five individual animals. *P ˂ 0.05, **P ˂ 0.01, ***P ˂ 0.001; ns. indicates not significant

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