Fig. 6

Vaccine-enriched clusters present at baseline. a In each of the nine participants, of the vaccine-specific clusters present at each post-vaccination time point (visit 2, 4, or 6), the percentage of these that were also present at baseline was determined. Mean ± SEM shown. b Correlation (Spearman) between the percentage of abundant clusters characterized as vaccine-specific and PC numbers determined by ELISpot, split according to whether the vaccine-specific clusters are also present at baseline. Different colored points represent samples from the different participants