Skip to main content
Fig. 2 | Genome Medicine

Fig. 2

From: Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation

Fig. 2

Chromatin dynamics and gene expression profiles from nuclear receptor activation. a The number of differentially regulated genes (up- and down-regulated) after 24 and 48 h of drug treatment (adjusted p < 0.01 and fold change cutoff ±2). b Gene Ontology connectivity map for GW3965 at 24 h for up-regulated (red) and down-regulated (red) pathways. c Gene Ontology connectivity map for GW3965 at 48 h for up-regulated (red) and down-regulated (red) pathways. d The number of H3K27ac sites gained (red) and lost (blue) after 24 and 48 h of GW3965 and rosiglitazone drug treatment

Back to article page