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Table 1 Total number of differentially regulated genes

From: Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation

 

24-h treatment

48-h treatment

 

Fold change ≥1.5

Fold change ≤ −1.5

Fold change ≥2

Fold change ≤ −2

Fold change ≥1.5

Fold change ≤ −1.5

Fold change ≥2

Fold change ≤ −2

Rosiglitazone

421

646

273

177

1019

1396

416

701

GW3965

223

83

100

24

1846

1646

698

535

T0901317

161

10

57

1

1538

1578

589

560

GW3965 + T0901317

119

5

47

0

1040

1141

357

395

  1. The total number of differentially regulated genes (up- and down-regulated) using two distinct fold change cutoffs (p < 0.01) from all drug treatments at 24- and 48-h time points is shown. For GW3965 + T0901317 high confidence LXR target gene analyses, all genes exceeded fold change and p value cutoffs across both drug treatments
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Genome Medicine

ISSN: 1756-994X

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