Fig. 3

QTL for pre-treatment phenotypes and candidate BMI genes. a QTL regions by phenotype. Shaded bounds depict the QTL regions identified as significant for each phenotype, with the colored bar displaying the QTL region maximum. Marker locations are indicated as gray bars across the chromosome. The level of shading indicates QTL directionality, with lightly shaded regions corresponding to QTL with heterozygous mice having lower mean phenotype values and heavily shaded regions corresponding to QTL with heterozygous mice having higher mean phenotype values. b BMI associated genes. Candidate genes that were significantly associated with BMI are plotted, along with their location on the chromosome. QTL regions are plotted in green, with the QTL peak as a thick dark line. Shading is assigned as in panel A