|
Attention deficit and hyperactivity disorder (ADHD)
|
2787/2635
|
–
|
–
|
[22]
|
|
Alzheimer's disease (ALZ)
|
17,008/37,154
|
7 (8)
|
2 (2)
|
[23]
|
|
Autism spectrum disorder (ASD)
|
13,088/16,664
|
–
|
–
|
[24]
|
|
Bipolar disorder (BIP1)
|
7481/9250
|
1 (1)
|
1 (1)
|
[25]
|
|
Major depressive disorder (MDD)
|
9240/9519
|
–
|
–
|
[26]
|
|
Inflammatory bowel disease (IBD)
|
12,882/21,770
|
37 (40)
|
14 (14)
|
[19]
|
|
Crohn's disease (CD)
|
5956/14,927
|
29 (33)
|
11 (12)
|
[19]
|
|
Ulcerative colitis (UC)
|
6968/20,464
|
17 (17)
|
6 (6)
|
[19]
|
|
Coronary artery disease (CAD)
|
60,801/123,504
|
9 (9)
|
5 (5)
|
[27]
|
|
Diastolic blood pressure (DBP)
|
69,395
|
5 (5)
|
–
|
[28]
|
|
Systolic blood pressure (SBP)
|
69,395
|
4 (4)
|
–
|
[28]
|
|
High-density lipoproteins (HDL)
|
93,561
|
38 (43)
|
12 (13)
|
[29]
|
|
Low-density lipoproteins (LDL)
|
89,138
|
28 (31)
|
6 (7)
|
[29]
|
|
Total cholesterol (TC)
|
93,845
|
40 (43)
|
8 (9)
|
[29]
|
|
Triglycerides (TG)
|
90,263
|
22 (25)
|
2 (2)
|
[29]
|
|
Type-2 diabetes (T2D)
|
12,171/56,862
|
–
|
–
|
[30]
|
|
Fasting glucose (FGLUCOSE)
|
38,422
|
4 (5)
|
–
|
[31]
|
|
Fasting insulin (FINSULIN)
|
23,823
|
–
|
–
|
[31]
|
|
Cigarettes per day (CIGPERDAY)
|
38,181
|
2 (3)
|
1 (2)
|
[32]
|
|
Ever smoked (EVERSMOKED)
|
74,035
|
–
|
–
|
[32]
|
|
College completion (COLLEGE) [33]
|
95,427
|
1 (1)
|
1 (1)
|
[33]
|
|
Education attainment (EDUYEARS)
|
101,069
|
3 (3)
|
3 (3)
|
[33]
|
|
Intelligence quotient (IQ)
|
17,989
|
–
|
–
|
[34]
|
|
Agreeableness (AGREE)
|
17,375
|
–
|
–
|
[35]
|
|
Conscientiousness (CONS)
|
17,375
|
–
|
–
|
[35]
|
|
Extraversion (EXTRAVERT)
|
17,375
|
–
|
–
|
[35]
|
|
Neuroticism (NEUROTIC)
|
63,661
|
–
|
–
|
[36, 37]
|
|
Openness (OPEN)
|
17,375
|
–
|
–
|
[35]
|
|
Total
| |
247 (271)
|
71 (77)
| |
