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Table 1 Top 20 differentially expressed genes following heat shock

From: Characterisation of the global transcriptional response to heat shock and the impact of individual genetic variation

Gene EntrezID logFC FC Average expression t p value Adjusted p value B
HSPA1B 3304 4.5 22.2 11.9 53.9 1.1E-52 1.4E-48 105.5
DNAJB1 3337 3.7 12.7 10.9 42.2 1.8E-46 1.1E-42 93.4
CLK1 1195 1.8 3.5 10.8 41.1 8.4E-46 3.5E-42 92.0
HSPA6 3310 4.2 18.3 9.4 29.9 7.8E-38 2.4E-34 75.2
HSPH1 10808 1.2 2.3 12.7 23.3 8.2E-32 2.0E-28 61.9
ZFAND2A 90637 1.9 3.8 9.5 23.2 9.8E-32 2.0E-28 61.8
TNFSF14 8740 1.4 2.7 9.4 23.0 1.4E-31 2.5E-28 61.4
HSPA6 3310 2.8 6.8 7.8 21.9 2.3E-30 3.6E-27 58.7
FXR1 8087 0.9 1.9 9.9 20.8 3.3E-29 4.5E-26 56.1
SERPINH1 871 1.9 3.7 8.7 20.4 8.6E-29 1.1E-25 55.2
TDG 6996 −0.9 0.5 10.7 −20.4 1.1E-28 1.2E-25 55.0
CCL3 6348 −1.3 0.4 11.4 −19.8 5.1E-28 5.2E-25 53.4
KIAA0907 22889 0.9 1.9 9.5 19.5 1.0E-27 9.9E-25 52.7
HSPA4L 22824 0.9 1.9 9.3 19.2 2.2E-27 2.0E-24 52.0
JUN 3725 1.2 2.3 9.2 19.0 3.5E-27 2.9E-24 51.5
CACYBP 27101 0.9 1.9 11.4 18.9 5.7E-27 4.2E-24 51.1
DNAJB4 11080 1.3 2.4 7.2 18.9 5.8E-27 4.2E-24 51.0
IER5 51278 1.4 2.6 10.5 18.1 4.3E-26 2.8E-23 49.1
LMAN2L 81562 0.8 1.7 8.4 18.1 4.9E-26 3.1E-23 48.9
BANP 54971 0.8 1.8 10.8 18.0 5.9E-26 3.47E-23 48.8
  1. The most significant differentially expressed genes for a panel of LCLs exposed to heat shock (42 °C for 1 h, 6 h recovery) and assayed by microarray are shown following limma analysis