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Table 1 Plasma lipids

From: Epigenomic and metabolic responses of hypothalamic POMC neurons to gestational nicotine exposure in adult offspring

Lipid (mg/dl)

Nicotine STD

Control STD

Nicotine HFD

Control HFD

Triglycerides

48.1 ± 5.4

44.6 ± 4.1

61.9 ± 5.4

67.0 ± 3.0*

Cholesterol

67.5 ± 3.1

64.7 ± 1.4

156.5 ± 12.3**

166.8 ± 4.7**

HDL-Cholesterol

50.6 ± 3.6

48.9 ± 1.3

124.3 ± 3.0**

125.9 ± 1.6**

VLDL-Cholesterol

9.6 ± 1.2

8.9 ± 0.8

12.4 ± 1.0

13.4 ± 0.6*

LDL-Cholesterol

5.2 ± 0.9

7.2 ± 1.1

27.3 ± 4.4**

27.5 ± 3.8**

  1. Plasma lipids were determined in week 16 of the diets following 14 h overnight fasting using VITROS® technology. Data were analyzed by two-way ANOVA followed by Bonferrroni post-test (*, p < 0.01; **, p < 0.001 versus STD feeding). Each group consisted of n = 6–9 male offspring from at least three different dams. Data are expressed as mean ± SEM. HDL High density lipoprotein, LDL Low density lipoprotein, VLDL Very low density lipoprotein
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Genome Medicine

ISSN: 1756-994X

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