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Table 3 Gene Ontology classification of protein-coding genes by molecular function

From: Epigenomic and metabolic responses of hypothalamic POMC neurons to gestational nicotine exposure in adult offspring

Category name (GO accession number)

Number of gene hits

Percent of gene hit against total number of genes

Percent of gene hit against total number of function hits

Antioxidant activity (GO:0016209)

18

0.20 %

0.10 %

Binding (GO:0005488)

3817

33.10 %

31.70 %

Catalytic activity (GO:0003824)

3763

32.70 %

31.20 %

Enzyme regulator activity (GO:0030234)

717

6.20 %

5.90 %

Nucleic acid binding transcription factor activity (GO:0001071)

1097

9.50 %

9.10 %

Protein binding transcription factor activity (GO:0000988)

147

1.30 %

1.20 %

Receptor activity (GO:0004872)

849

7.40 %

7.00 %

Structural molecule activity (GO:0005198)

786

6.80 %

6.50 %

Translation regulator activity (GO:0045182)

116

1.00 %

1.00 %

Transporter activity (GO:0005215)

745

6.50 %

6.20 %

  1. PANTHER classified 12,731 protein-coding genes with average expression values > 1 CPM by molecular function. A total of 13,395 molecular functions were hit
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Genome Medicine

ISSN: 1756-994X

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