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Fig. 3 | Genome Medicine

Fig. 3

From: Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series

Fig. 3

Genetic mapping of genome-wide gene expression in the adipose tissue of BN.GK congenic rats derived for chromosome 1 loci. Quantitative trait locus (QTL) mapping was applied to define regions of chromosome 1 showing evidence of statistically significant (LOD >5) linkage with changes in the transcription of genes localized in genomic regions defined by GK haplotypes (putative cis-acting eQTL effects) or outside the regions (trans-acting eQTL effects). Details of the congenic strains and congenic-defined regions are given in Table 1 and associated transcripts in Additional file 3: Table S4. The localization of genes regulated in trans is indicated in parentheses

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