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Table 2 Summary of metabolites detected in 1H NMR spectra from adipose tissue extracts of congenic rats and BN controls

From: Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series

Metabolite 1H chemical shift (δ, ppm) and multiplicity
Formate 8.46 (s)
Inosinea 8.34 (s), 8.23 (s), 6.1 (d), 4.44 (t)
Non-assigned 8.27 (s)
Non-assigneda 7.68 (s)
Inosine-diphosphate 6.16 (s)
Allantoina 5.4 (s)
Lipids (C[H2]-CH2-CO) 5.31 (m)
Glucosea 5.23 (m), 3.84
Glycerophosphocholinea 4.32 (m), 3.23 (s)
Lactatea 4.11 (q), 1.33 (d)
Myo-inositol 4.06 (t), 3.61 (dd), 3.52 (dd)
Creatine 3.93 (s), 3.04 (s)
β-D-glucosea 3.91 (dd), 3.73 (d), 3.48 (m)
Glycerola 3.78 (m), 3.66 (dd), 3.64 (dd), 3.56 (dd)
3-Methyl-histidinea 3.7 (s)
Taurine 3.42 (t)a 3.42 (t), 3.25 (t)
Scyllo-inositola 3.36 (s)
Cholinea 3.21 (s)
Non-assigned 3.13 (s), 4.04 (d)
Lipids (C = C-CH2-C = C) 2.76 (m)
Glutaminea 2.46 (m), 2.14 (m)
Succinatea 2.41 (s)
Glutamatea 2.36 (dt), 2.04 (m)
3-Hydroxybutyratea 2.31 (m), 1.2 (d)
Lipids (CH2-CO) 2.26 (m)
N-acetylglutaminea 2.02 (s)
Acetatea 1.92 (s)
Lipids (C[H2]-CH2-CO) 1.58 (m)
Alanine 1.48 (d)
Lipids ((−CH2-)n) 1.27 (m)
Valine 1.04 (d), 0.99 (d)
Isoleucinea 1.01 (d)
Leucine 0.96 (dd)
Lipids (CH3) 0.89 (m)
  1. aCompounds that were statistically significant (P < 0.05) between at least a congenic strain and BN. Patterns of significant differential regulation of these metabolites in the relevant congenic strains and contributing chromosomal regions are shown in Fig. 2
  2. S singlet, d doublet, t triplet, m multiplet, dd doublet of doublet, dt doublet of triplet