TY - JOUR AU - Chen, Jun AU - Toyomasu, Yoshitaka AU - Hayashi, Yujiro AU - Linden, David R. AU - Szurszewski, Joseph H. AU - Nelson, Heidi AU - Farrugia, Gianrico AU - Kashyap, Purna C. AU - Chia, Nicholas AU - Ordog, Tamas PY - 2016 DA - 2016/10/03 TI - Altered gut microbiota in female mice with persistent low body weights following removal of post-weaning chronic dietary restriction JO - Genome Medicine SP - 103 VL - 8 IS - 1 AB - Nutritional interventions often fail to prevent growth failure in childhood and adolescent malnutrition and the mechanisms remain unclear. Recent studies revealed altered microbiota in malnourished children and anorexia nervosa. To facilitate mechanistic studies under physiologically relevant conditions, we established a mouse model of growth failure following chronic dietary restriction and examined microbiota in relation to age, diet, body weight, and anabolic treatment. SN - 1756-994X UR - https://doi.org/10.1186/s13073-016-0357-1 DO - 10.1186/s13073-016-0357-1 ID - Chen2016 ER -