Skip to main content

Table 2 Relative contribution of age, diet, and weight to the overall microbiota variabilitya

From: Altered gut microbiota in female mice with persistent low body weights following removal of post-weaning chronic dietary restriction

Distanceb

Age

Diet

Weight

Total

R2 c

P valued

R2

P value

R2

P value

R2

P value

UniFrac

7.3 %

<0.001

1.8 %

<0.001

0.6 %

0.429

14.4 %

<0.001

GUniFrac

6.4 %

<0.001

3.6 %

<0.001

1.4 %

0.167

15.4 %

<0.001

WUniFrac

6.9 %

0.003

3.8 %

0.008

1.1 %

0.139

15.5 %

<0.001

  1. aBased on ad libitum-fed (AL) and limited-fed (LF) diet groups
  2. bUniFrac, GUniFrac, and WUniFrac represent unweighted, generalized (α = 0.5), and weighted UniFrac distance, respectively
  3. cR2 represents the percentage of microbiota variability explained by corresponding covariate adjusting for other covariates
  4. dSignificance was assessed based on 1000 permutations. For age and weight, permutation was confined within each subject