Distanceb
| Age | Diet | Weight | Total |
---|
R2 c
|
P valued
| R2
|
P value | R2
|
P value | R2
|
P value |
---|
UniFrac | 7.3Â % | <0.001 | 1.8Â % | <0.001 | 0.6Â % | 0.429 | 14.4Â % | <0.001 |
GUniFrac | 6.4Â % | <0.001 | 3.6Â % | <0.001 | 1.4Â % | 0.167 | 15.4Â % | <0.001 |
WUniFrac | 6.9Â % | 0.003 | 3.8Â % | 0.008 | 1.1Â % | 0.139 | 15.5Â % | <0.001 |
-
aBased on ad libitum-fed (AL) and limited-fed (LF) diet groups
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bUniFrac, GUniFrac, and WUniFrac represent unweighted, generalized (α = 0.5), and weighted UniFrac distance, respectively
-
cR2 represents the percentage of microbiota variability explained by corresponding covariate adjusting for other covariates
-
dSignificance was assessed based on 1000 permutations. For age and weight, permutation was confined within each subject