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Fig. 4 | Genome Medicine

Fig. 4

From: MIPEP recessive variants cause a syndrome of left ventricular non-compaction, hypotonia, and infantile death

Fig. 4

In organello processing activity of Oct1L339F and Oct1K376E mutants. a–c In vitro import and processing of radiolabeled Mdh1, Cox4, and Mrp21 preproteins in isolated mitochondria (Mito.) from indicated mutant strains compared to wild type (Oct1 WT). d In vitro import and processing of the Oct1-independent preprotein Atp2. The reaction was performed as in a–c. Δψ is the mitochondrial membrane potential. i processing intermediate, m mature protein, p precursor

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