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Table 1 The contribution of genomic information to precision cancer medicine

From: Integrating precision cancer medicine into healthcare—policy, practice, and research challenges

The contribution of genomic information to precision cancer medicine Typical example(s)
Cancer risk reduction Genetic testing of BRCA1/BRCA2 in hereditary breast cancer and ovarian cancer; MSH2/MSH6/MLH in hereditary nonpolyposis colorectal cancer; RB1 in retinoblastoma
Early detection Liquid biopsies
Accurate diagnosis Using molecular markers in tumor classification
Targeted therapy EGFR inhibitors to treat EGFR mutation carriers; BRAF inhibitors to treat BRAF V600E carriers; Tyrosine-kinase inhibitor to treat BCR–ABL fusion protein