Skip to main content

Table 1 Patient demographics

From: Potential contribution of the uterine microbiome in the development of endometrial cancer

Variables Benign (n = 10) Cancer (n = 17) p value Hyperplasia (n = 4) p value vs. benign p value vs. cancer
Age (years) – Median, IQR 44.5 (42.5–52.5) 64 (58–71) 0.0001 54 (50.75–62.5) 0.0552 0.08
Caucasian ethnicity (%) 10 (100) 17 (100)   4 (100)   
BMI – Median, IQR 26.6 (23.8–34.1) 32.1 (26.8–40.2) 0.07 35.4 (24–40.8) 0.29 0.89
Menopausal status    0.0034   >0.99 0.0526
Pre/Peri 8 3   3   
Post 2 14   1   
Gravida – Median, IQR 2 (2–3.25) 1.5 (0–4) 0.666 0 (0–2.25) 0.1 0.19
Parity – Median, IQR 2 (2–3) 1.5 (0–4) 0.569 0 (0–2.25) 0.13 0.23
History of hypertension    0.0362   0.85 0.31
 Yes 1 10   1   
 No 8 7   3   
 Unknown 1 0   0   
History of diabetes    0.621   >0.99 0.54
 Yes 1 4   0   
 No 9 13   4   
Smoking status    0.5911   0.46 0.75
 Never smoker 5 9   3   
 Previous smoker 2 4   1   
 Current smoker 3 2   0   
 Unknown 0 2   0   
Vaginal pH    0.0053   >0.99 0.07
 Normal 6 1   2   
 High 4 15   2   
 Unknown 0 1   0   
Histotype (%)       
 Endometrioid adenocarcinoma - 11 (64.7)   -   
 Serous adenocarcinoma - 3 (17.6)   -   
 Mucinous adenocarcinoma - 1 (5.9)   -   
 Squamous adenocarcinoma - 1 (5.9)   -   
 Carcinosarcoma - 1 (5.9)   -   
Grade (%)       
 Grade 1/Grade 2 - 13 (76.5)   -   
 Grade 3 - 4 (23.5)   -   
Stage (%)       
 I - 13 (76.5)   -   
 III/IV - 4 (23.5)   -   
  1. BMI body mass index, IQR interquartile range