Table 1 Patient demographics
From: Potential contribution of the uterine microbiome in the development of endometrial cancer
| Variables | Benign (n = 10) | Cancer (n = 17) | p value | Hyperplasia (n = 4) | p value vs. benign | p value vs. cancer |
|---|---|---|---|---|---|---|
| Age (years) – Median, IQR | 44.5 (42.5–52.5) | 64 (58–71) | 0.0001 | 54 (50.75–62.5) | 0.0552 | 0.08 |
| Caucasian ethnicity (%) | 10 (100) | 17 (100) | 4 (100) | |||
| BMI – Median, IQR | 26.6 (23.8–34.1) | 32.1 (26.8–40.2) | 0.07 | 35.4 (24–40.8) | 0.29 | 0.89 |
| Menopausal status | 0.0034 | >0.99 | 0.0526 | |||
| Pre/Peri | 8 | 3 | 3 | |||
| Post | 2 | 14 | 1 | |||
| Gravida – Median, IQR | 2 (2–3.25) | 1.5 (0–4) | 0.666 | 0 (0–2.25) | 0.1 | 0.19 |
| Parity – Median, IQR | 2 (2–3) | 1.5 (0–4) | 0.569 | 0 (0–2.25) | 0.13 | 0.23 |
| History of hypertension | 0.0362 | 0.85 | 0.31 | |||
| Yes | 1 | 10 | 1 | |||
| No | 8 | 7 | 3 | |||
| Unknown | 1 | 0 | 0 | |||
| History of diabetes | 0.621 | >0.99 | 0.54 | |||
| Yes | 1 | 4 | 0 | |||
| No | 9 | 13 | 4 | |||
| Smoking status | 0.5911 | 0.46 | 0.75 | |||
| Never smoker | 5 | 9 | 3 | |||
| Previous smoker | 2 | 4 | 1 | |||
| Current smoker | 3 | 2 | 0 | |||
| Unknown | 0 | 2 | 0 | |||
| Vaginal pH | 0.0053 | >0.99 | 0.07 | |||
| Normal | 6 | 1 | 2 | |||
| High | 4 | 15 | 2 | |||
| Unknown | 0 | 1 | 0 | |||
| Histotype (%) | ||||||
| Endometrioid adenocarcinoma | - | 11 (64.7) | - | |||
| Serous adenocarcinoma | - | 3 (17.6) | - | |||
| Mucinous adenocarcinoma | - | 1 (5.9) | - | |||
| Squamous adenocarcinoma | - | 1 (5.9) | - | |||
| Carcinosarcoma | - | 1 (5.9) | - | |||
| Grade (%) | ||||||
| Grade 1/Grade 2 | - | 13 (76.5) | - | |||
| Grade 3 | - | 4 (23.5) | - | |||
| Stage (%) | ||||||
| I | - | 13 (76.5) | - | |||
| III/IV | - | 4 (23.5) | - |
