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Table 1 Patient demographics

From: Potential contribution of the uterine microbiome in the development of endometrial cancer

Variables

Benign (n = 10)

Cancer (n = 17)

p value

Hyperplasia (n = 4)

p value vs. benign

p value vs. cancer

Age (years) – Median, IQR

44.5 (42.5–52.5)

64 (58–71)

0.0001

54 (50.75–62.5)

0.0552

0.08

Caucasian ethnicity (%)

10 (100)

17 (100)

 

4 (100)

  

BMI – Median, IQR

26.6 (23.8–34.1)

32.1 (26.8–40.2)

0.07

35.4 (24–40.8)

0.29

0.89

Menopausal status

  

0.0034

 

>0.99

0.0526

Pre/Peri

8

3

 

3

  

Post

2

14

 

1

  

Gravida – Median, IQR

2 (2–3.25)

1.5 (0–4)

0.666

0 (0–2.25)

0.1

0.19

Parity – Median, IQR

2 (2–3)

1.5 (0–4)

0.569

0 (0–2.25)

0.13

0.23

History of hypertension

  

0.0362

 

0.85

0.31

 Yes

1

10

 

1

  

 No

8

7

 

3

  

 Unknown

1

0

 

0

  

History of diabetes

  

0.621

 

>0.99

0.54

 Yes

1

4

 

0

  

 No

9

13

 

4

  

Smoking status

  

0.5911

 

0.46

0.75

 Never smoker

5

9

 

3

  

 Previous smoker

2

4

 

1

  

 Current smoker

3

2

 

0

  

 Unknown

0

2

 

0

  

Vaginal pH

  

0.0053

 

>0.99

0.07

 Normal

6

1

 

2

  

 High

4

15

 

2

  

 Unknown

0

1

 

0

  

Histotype (%)

      

 Endometrioid adenocarcinoma

-

11 (64.7)

 

-

  

 Serous adenocarcinoma

-

3 (17.6)

 

-

  

 Mucinous adenocarcinoma

-

1 (5.9)

 

-

  

 Squamous adenocarcinoma

-

1 (5.9)

 

-

  

 Carcinosarcoma

-

1 (5.9)

 

-

  

Grade (%)

      

 Grade 1/Grade 2

-

13 (76.5)

 

-

  

 Grade 3

-

4 (23.5)

 

-

  

Stage (%)

      

 I

-

13 (76.5)

 

-

  

 III/IV

-

4 (23.5)

 

-

  
  1. BMI body mass index, IQR interquartile range