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Table 3 Significant bacterial genera between benign and endometrial cancer cohorts

From: Potential contribution of the uterine microbiome in the development of endometrial cancer

Combined q < 0.10 Value Standard error Degrees of freedom t value p value q value Test
Firmicutes; Anaerostipes 3.4 0.795 25 4.3 0.0002 0.017 Presence/absence
Firmicutes; ph2 3.1 0.829 25 3.7 0.0010 0.031 Presence/absence
Spirochaetes; Treponema 3.9 1.066 25 3.7 0.0011 0.031 Presence/absence
Actinobacteria; Atopobium 2.5 0.707 25 3.5 0.0017 0.036 Presence/absence
Bacteroidetes; Bacteroides 1.1 0.332 25 3.3 0.0026 0.044 Counts
Proteobacteria; Arthrospira 3.6 1.150 25 3.1 0.0044 0.062 Presence/absence
Firmicutes; Dialister 1.2 0.405 25 3.0 0.0061 0.073 Presence/absence
Firmicutes; Peptoniphilus 1.4 0.494 25 2.9 0.0074 0.075 Presence/absence
Firmicutes; 1-68 1.3 0.465 25 2.9 0.0080 0.075 Presence/absence
Firmicutes; Ruminococcus 0.9 0.319 25 2.8 0.0109 0.082 Counts
Bacteroidetes; Porphyromonas 1.8 0.664 25 2.7 0.0111 0.082 Presence/absence
Firmicutes; Anaerotruncus 1.3 0.477 25 2.7 0.0117 0.082 Presence/absence
  1. Significant bacterial genera between benign and endometrial cancer cohorts in the vaginal, cervical, and endometrial microbiome as determined by generalized mixed effect model (FDR q < 0.10). All genera are enriched in the endometrial cancer cohort