Skip to main content

Table 4 SNPs with differential allele-specific expression in LA compared to LV

From: Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia

Ā Ā Ā Ā 

LA

LV

Differential ASE LA vs. LV

SNP

Gene

Chr

Location

Samples

REF/ALTā€‰+ā€‰REF

FDR-adj. p value

Samples

REF/ALTā€‰+ā€‰REF

FDR-adj. p value

FDR-adj. p value

rs137831

ACO2

22

41,903,813

43

0.96

4ā€‰Ć—ā€‰10ā€“99

24

0.47

0.79

1ā€‰Ć—ā€‰10ā€“75

rs6816298

TECRL

4

65,144,051

17

0.39

0.001

25

0.68

4ā€‰Ć—ā€‰10ā€“7

1ā€‰Ć—ā€‰10ā€“29

rs1128416

PPP1CB

2

29,001,691

30

0.48

3ā€‰Ć—ā€‰10ā€“5

31

0.32

1ā€‰Ć—ā€‰10ā€“34

2ā€‰Ć—ā€‰10ā€“26

rs1046138

PKP2

12

32,944,162

32

0.84

1ā€‰Ć—ā€‰10ā€“253

32

0.92

8ā€‰Ć—ā€‰10ā€“194

8ā€‰Ć—ā€‰10ā€“18

rs7292

MB

22

36,007,045

36

0.56

3ā€‰Ć—ā€‰10ā€“123

35

0.51

1

1ā€‰Ć—ā€‰10ā€“16

rs2531332

RPL3L

16

1,994,749

33

0.62

2ā€‰Ć—ā€‰10ā€“39

38

0.51

0.97

3ā€‰Ć—ā€‰10ā€“15

rs201567919

ADAR

1

154,556,764

26

0.72

2ā€‰Ć—ā€‰10ā€“52

38

0.59

1ā€‰Ć—ā€‰10ā€“8

2ā€‰Ć—ā€‰10ā€“13

rs1063281

TNS1

2

218,668,732

46

0.53

0.13

39

0.46

0.003

5ā€‰Ć—ā€‰10ā€“12

rs7508

ASAH1

8

17,913,970

21

0.72

1ā€‰Ć—ā€‰10ā€“83

38

0.56

0.03

1ā€‰Ć—ā€‰10ā€“11

rs61756583

OGDH

7

44,747,514

4

0.65

2ā€‰Ć—ā€‰10ā€“10

6

0.80

2ā€‰Ć—ā€‰10ā€“68

3ā€‰Ć—ā€‰10ā€“9

  1. The table shows the ten SNPs with the most significantly different ASE in the LA compared to LV samples (baseline pre-ischemia). Shown is the gene the SNP is located within, the genomic location, number of heterozygous samples for both LA and LV, the REF/ALTā€‰+ā€‰REF ratio, the p value for ASE calling, and finally the FDR-adjusted p value for the test of differential ASE between LA and LV tissues