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Table 4 SNPs with differential allele-specific expression in LA compared to LV

From: Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia

     LA LV Differential ASE LA vs. LV
SNP Gene Chr Location Samples REF/ALT + REF FDR-adj. p value Samples REF/ALT + REF FDR-adj. p value FDR-adj. p value
rs137831 ACO2 22 41,903,813 43 0.96 4 × 10–99 24 0.47 0.79 1 × 10–75
rs6816298 TECRL 4 65,144,051 17 0.39 0.001 25 0.68 4 × 10–7 1 × 10–29
rs1128416 PPP1CB 2 29,001,691 30 0.48 3 × 10–5 31 0.32 1 × 10–34 2 × 10–26
rs1046138 PKP2 12 32,944,162 32 0.84 1 × 10–253 32 0.92 8 × 10–194 8 × 10–18
rs7292 MB 22 36,007,045 36 0.56 3 × 10–123 35 0.51 1 1 × 10–16
rs2531332 RPL3L 16 1,994,749 33 0.62 2 × 10–39 38 0.51 0.97 3 × 10–15
rs201567919 ADAR 1 154,556,764 26 0.72 2 × 10–52 38 0.59 1 × 10–8 2 × 10–13
rs1063281 TNS1 2 218,668,732 46 0.53 0.13 39 0.46 0.003 5 × 10–12
rs7508 ASAH1 8 17,913,970 21 0.72 1 × 10–83 38 0.56 0.03 1 × 10–11
rs61756583 OGDH 7 44,747,514 4 0.65 2 × 10–10 6 0.80 2 × 10–68 3 × 10–9
  1. The table shows the ten SNPs with the most significantly different ASE in the LA compared to LV samples (baseline pre-ischemia). Shown is the gene the SNP is located within, the genomic location, number of heterozygous samples for both LA and LV, the REF/ALT + REF ratio, the p value for ASE calling, and finally the FDR-adjusted p value for the test of differential ASE between LA and LV tissues