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Table 5 SNPs with differential allele-specific expression in the LA for patients with poAF

From: Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia

Ā Ā Ā Ā Ā 

poAF

No poAF

Ā 

SNP

Gene

Chr

Location

Reads

Samples

REF/ALTā€‰+ā€‰REF

Samples

REF/ALTā€‰+ā€‰REF

FDR-adjusted p value

rs2230287

GSN

9

124,065,224

10,279

1

1.00

2

0.50

1ā€‰Ć—ā€‰10ā€“67

rs41267649

CUTA

6

33,384,473

576

1

1.00

2

0.48

4ā€‰Ć—ā€‰10ā€“40

rs3733570

QDPR

4

17,503,433

538

3

0.46

1

1.00

4ā€‰Ć—ā€‰10ā€“28

rs114068468

HLA-DPB1

6

33,054,463

572

2

0.55

1

1.00

6ā€‰Ć—ā€‰10ā€“26

rs2241198

IGFBP5

2

217,539,068

642

1

1.00

3

0.52

2ā€‰Ć—ā€‰10ā€“25

rs11550240

COX8A

11

63,743,756

4318

1

0.56

1

1.00

2ā€‰Ć—ā€‰10ā€“20

rs1800215

COL1A1

17

48,265,495

688

2

0.57

1

0.03

1ā€‰Ć—ā€‰10ā€“19

rs200375051

C7

5

40,972,534

1081

1

0.51

3

1.00

8ā€‰Ć—ā€‰10ā€“19

rs3762568

FASTKD2

2

207,631,461

518

1

1.00

6

0.51

5ā€‰Ć—ā€‰10ā€“18

rs45555133

DACT3

19

47,151,717

288

3

0.49

2

1.00

9ā€‰Ć—ā€‰10ā€“17

rs117770959

ZMIZ2

7

44,807,772

207

3

0.48

1

1.00

1ā€‰Ć—ā€‰10ā€“8

rs118077107

NEURL4

17

7,221,197

176

1

1.00

4

0.46

5ā€‰Ć—ā€‰10ā€“8

rs74450883

FAM219B

15

75,193,432

361

2

0.48

1

1.00

9ā€‰Ć—ā€‰10ā€“7

rs56173620

LAMA2

6

129,722,453

460

2

0.51

1

1.00

2ā€‰Ć—ā€‰10ā€“6

rs11538698

MGLL

3

127,540,635

662

1

0.49

4

1.00

4ā€‰Ć—ā€‰10ā€“5

rs79181968

SERPINA3

14

95,080,814

254

1

1.00

3

0.60

9ā€‰Ć—ā€‰10ā€“5

rs12117552

LMNA

1

156,104,292

886

1

0.50

1

1.00

0.002

kgp10133162

CLDN18

3

137,750,586

188

3

0.11

5

0.60

0.004

rs138684608

TMED10

14

75,643,107

693

1

0.46

1

1.00

0.005

rs147227072

PCOLCE2

3

142,567,193

685

1

0.53

1

1.00

0.007

rs61741262

TNS1

2

218,669,225

3070

3

0.43

9

0.52

0.01

rs574774

ASAH1

8

17,914,883

3591

1

0.68

2

0.76

0.02

rs4280262

LITAF

16

11,647,492

1801

7

0.45

10

0.57

0.04

  1. The table shows the SNPs with different ASE in the LA in patients who had poAF compared with those who did not. Shown is the gene the SNP is located within, the genomic location, number of reads overlapping the SNP, number of heterozygous LA samples for both patient groups, the REF/ALTā€‰+ā€‰REF ratio, and the FDR-adjusted p value for differential ASE between the two patient groups