Fig. 3

Summary of informative results from the PIPseq program. A matrix representation of findings with biological significance from the sequencing results are presented. Data are derived from all 101 patients that underwent WES of tumor-normal sample pairs, exome sequencing of germline DNA, transcriptome analysis of tumor, CNV of tumor, and targeted panel sequencing of tumor only. Deleterious mutations were loss of function mutations and activating mutations refers to recurrent, previously reported activating mutations in oncogenes or variants with published in vitro evidence as being activating