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Table 1 Association of rs612529 with AD

From: A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus

Referencesa Populationb Casesc (n) Controlsd (n) Effect allelee Effect allele frequencyf OR (95% CI)g P valueh
[15] Caucasian 1200 2270 C 0.209 1.12 (1.15–1.29) 1.26 × 10–3
[14] Chinese 1012 1362 C 0.322 1.15 (1.07–1.30) 2.6 × 10–2
[12, 13] Chinese 324 486 C 0.36 1.29 (1.10–1.45) 4 × 10–6
  Combined 2536 4118     1.14 × 10 –6
  1. aInitial study describing the cohorts used for association
  2. bEthnicity of the population under study
  3. cNumber of atopic dermatitis cases
  4. dNumber of controls
  5. eAllele used for the calculating the odds ratio statistics
  6. fAllele frequency of the effect allele in the individual study population
  7. gOdds ratio estimated with 95% confidence interval
  8. h P value estimated for the case control association study for atopic dermatitis phenotype in the individual study population
  9. Meta P value is the P value calculated for all three cohorts combined using the Stoufier’s z trend meta-analysis which considers individual study P value sample sizes and effect directions using Meta P program [20]