From: Microbiomic differences in tumor and paired-normal tissue in head and neck squamous cell carcinomas
Variable | Included (n = 121) | Excluded (n = 38) | p value |
---|---|---|---|
Age (years) | 63 ± 11 | 62 ± 13 | 0.73 |
Male | 74 (64) | 25 (74) | 0.31 |
Race | 0.07 | ||
White | 71 (91) | 19 (100) | |
Black | 7 (9) | 0 (0) | |
Localization | 0.32 | ||
Oral cavity/Oropharynx | 72 (65) | 26 (74) | |
Floor of mouth | 5 | 2 | |
Tongue | 42 | 11 | |
Tonsil | 13 | 8 | |
Oral cavity NOS | 12 | 5 | |
Hypopharynx/Larynx | 38 (35) | 9 (26) | |
Hypopharynx | 4 | 2 | |
Larynx | 34 | 7 | |
T-stage | 0.59 | ||
Low T-stage | 44 (40) | 15 (45) | |
T0 | 4 | 2 | |
T1–T2 | 42 | 13 | |
High T-stage (T3–T4) | 66 (60) | 18 (55) | |
N-stage | 0.58 | ||
Node negative (N0) | 56 (51) | 15 (45) | |
Node positive | 54 (48) | 18 (55) | |
N1–N2 | 51 | 18 | |
N3 | 3 | 0 | |
Overall stage | 0.16 | ||
I–II | 24 (24) | 4 (13) | |
III–IV | 78 (76) | 28 (88) | |
Previous treatment | |||
Operation | 21 (19) | 4 (12) | 0.37 |
Chemotherapy | 24 (21) | 3 (9) | 0.09 |
Radiotherapy | 30 (26) | 8 (24) | 0.78 |
Smoking history | 0.08 | ||
Current | 18 (16) | 1 (3) | |
Past | 68 (60) | 24 (71) | |
Never | 29 (25) | 9 (26) | |
Alcohol use | 0.96 | ||
Heavy | 10 (9) | 4 (12) | |
Social | 57 (50) | 16 (47) | |
History | 10 (9) | 3 (9) | |
Never | 37 (32) | 11 (32) |