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Fig. 2 | Genome Medicine

Fig. 2

From: Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

Fig. 2

Genome-wide expression responses to IMQ. a, b Imiquimod principal component response vectors for a males and b females (arrow start, CTL sample average; arrow end, IMQ sample average). c Spearman correlations between fold change (FC) estimates (IMQ/CTL). d Comparison of FC estimates (IMQ/CTL) of each strain to B6 mice of the same sex (top, males; bottom, females; white font, Spearman correlation coefficient). Colors reflect gene density (see scale). e Self-organizing maps (SOMs). Genes are plotted on the same SOM for each sex/strain and the color scale denotes FC (IMQ/CTL). F female, M male

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