Fig. 5
From: Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis
Cytokine, chemokine, and cluster of differentiation gene expression. a–c Genes encoding cytokines (a), cluster of differentiation proteins (b), and chemokines (c). d Genes induced by IL-17 family cytokines (human KCs). Heatmap colors depict average IMQ response of 50 genes most strongly induced in each experiment (left margin; *HaCaT; **reconstituted epidermis; cytokine concentration and exposure time shown in parentheses). e Genes most frequently induced in six experiments from d in which KCs were treated with IL-17A alone. F female, FC fold change, M male, PN uninvolved skin from psoriasis patients, PP lesional skin from psoriasis patients