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Fig. 5 | Genome Medicine

Fig. 5

From: Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

Fig. 5

Cytokine, chemokine, and cluster of differentiation gene expression. ac Genes encoding cytokines (a), cluster of differentiation proteins (b), and chemokines (c). d Genes induced by IL-17 family cytokines (human KCs). Heatmap colors depict average IMQ response of 50 genes most strongly induced in each experiment (left margin; *HaCaT; **reconstituted epidermis; cytokine concentration and exposure time shown in parentheses). e Genes most frequently induced in six experiments from d in which KCs were treated with IL-17A alone. F female, FC fold change, M male, PN uninvolved skin from psoriasis patients, PP lesional skin from psoriasis patients

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