Table 1 Patient characteristics of the head and neck cancers for which DNA methylome data were analysed
From: Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas
Patient characteristics | HPV positive No. cases (%)a | HPV negative No. cases (%)a |
|---|---|---|
Pooled cases | 66 (100) | 272 (100) |
TCGA | 36 (54.5) | 242 (89.0) |
UCL | 24 (21 FFPE) (36.4) | 24 (21 FFPE (8.8) |
FITMANET | 6 (9.1) | 6 (2.2) |
Male | 55 (83.3) | 195 (71.7) |
Female | 11 (17.7) | 77 (28.3) |
Median age (range) | 59 (35–86) | 62 (19–90) |
Tobacco smoking | ||
Never/light smokers | 17 (25.7) | 54 (19.8) |
Smokers | 25 (37.9) | 218 (80.0) |
Not available | 24 (36.4) | 25 (9.2) |
Alcohol consumption | ||
No | 9 (13.6) | 83 (30.5) |
Yes | 32 (48.5) | 159 (58.5) |
Not available | 25 (37.9) | 30 (11.0) |
Tumour stage | ||
T1 | 8 (12.1) | 13 (4.8) |
T2 | 19 (28.8) | 49 (18.0) |
T3 | 9 (13.6) | 64 (23.5) |
T4 (A + B) | 28 (42.4) | 118 (43.4) |
Not available | 2 (3.1) | 28 (10.3) |
Tumour site | ||
Oral cavity | 12 (18.2)b | 162 (59.5) |
Oropharynx | 51 (77.3)c | 35 (12.9) |
Neck (hypopharynx and larynx) | 3 (4.5)d | 75 (27.6) |