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Fig. 3 | Genome Medicine

Fig. 3

From: Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma

Fig. 3

Log2-transformed NUMT proportions in tumor and blood-derived normal (Pij) genomes. a Log2-transformed NUMT proportions in tumor and normal genomes showcasing the difference in their means, indicating higher NUMT distribution in tumor genomes compared to matched blood-derived normal genomes. A two-tailed paired t-test conducted between the log2-transformed NUMT proportions for 57 samples revealed a P value of 1.87 × 10−11, showing significant difference in the log-transformed NUMT proportions between primary tumors and blood-derived normal genomes. b Relationship between abundance measures of blood-derived normal genome NUMTs and tumor genome NUMTs showing a positive relationship with R2 = 0.17 and P value = 0.0016

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