Fig. 4
From: Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma
NUMT abundance across disease–sex combination. Colorectal tumors from women have higher NUMT abundance proportion (tumor NUMT/blood normal NUMT) than those from men. Women had a median NUMT fold change abundance of 4.52 (range 0.11 to 22.9) compared 3.1 for men (range 0.53 to 8.3). COAD colon adenocarcinoma, READ rectum adenocarcinoma. To investigate the sex difference in the NUMT abundances, an unequal variance t-test was performed on the raw NUMT proportions observed by the members of the two sex groups stratified by “blood-normal” and “primary tumor” classifications. The P value was 0.03 between males (N = 23) and females (N = 34) for blood-derived normal samples and 0.08 for tumor samples