Skip to main content
Fig. 6 | Genome Medicine

Fig. 6

From: Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma

Fig. 6

NUMT density in tumor and normal genomes (sorted by disease (T2), sex (T1), and age at initial pathologic diagnosis (T3)). Each peripheral node represents a TCGA sample whose blood-derived normal and tumor genomes were used in this study. From the outside to inside, tracks are ordered from 1 to 7 (T1–T7). T1: Sample sex where red nodes represent female and blue nodes represent male. T2: Disease type information. Rectal adenocarcinoma (READ) is rendered as green bands and colon adenocarcinoma (COAD) as red bands. T3: Age at initial pathologic diagnosis ranging from 30 to 90 years. White and black filled bars represent white and black race, respectively. T4: Red columns represent NUMT proportion in tumor genomes and green columns represent blood-derived normal NUMT proportion. T5: Vital status of the patients where red indicates deceased individuals and green alive status. T6: Stage of tumor represented in grey-scale—stage I white, stage II grey, stage III dark grey, and stage IV black. T7: Fold-change in NUMT abundance. Samples at <1-fold are rendered as colored bands; 1–4-fold, blue; 4–8-fold, green; 8–12-fold, yellow; 12–20-fold, orange; and >20-fold, red

Back to article page