Table 1 Interaction effects on tRNA p9 site methylation
From: Integrated genomic analysis of mitochondrial RNA processing in human cancers
Cancer | p9 Site | rs number | Chr | Position | Location | Gene | N | MAF | MAF range | P value |
|---|---|---|---|---|---|---|---|---|---|---|
BRCA | 7526 | rs3781574 | 11 | 33885268 | intron | LMO2 | 46 | 0.161 | 0.128–0.231 | 4.61E-11 |
BRCA | 7526 | rs17690328 | 11 | 33885390 | intron | LMO2 | 46 | 0.135 | 0.016–0.190 | 1.17E-08 |
BRCA | 7526 | rs317391 | 17 | 32174605 | intron | ASIC2 | 44 | 0.085 | 0.014–0.485 | 2.46E-09 |
KIRC | 1610 | rs258701 | 7 | 81761122 | intron | CACNA2D1 | 61 | 0.058 | 0.072–0.167 | 8.27E-10 |
KIRC | 8303 | rs10266772 | 7 | 14132727 | Intergenic | - | 61 | 0.080 | 0.079–0.254 | 2.27E-08 |
KIRC | 10413 | rs1028014 | 8 | 40698232 | intron | ZMAT4 | 64 | 0.174 | 0.085–0.236 | 2.88E-08 |
KIRC | 12146 | rs17164416 | 5 | 99387447 | Intergenic | - | 65 | 0.051 | 0.000–0.188 | 9.95E-09 |
LIHC | 12146 | rs41465346 | 1 | 219059708 | Intergenic | - | 48 | 0.052 | 0.006–0.304 | 3.73E-08 |
LIHC | 12146 | rs16926871 | 8 | 62027498 | intron | CLVS1 | 47 | 0.074 | 0.038–0.270 | 1.24E-08 |
LUAD | 585 | rs13029285 | 2 | 205916078 | intron | PARD3B | 49 | 0.057 | 0.003–0.076 | 1.81E-10 |
LUAD | 10413 | rs7328699 | 13 | 28615701 | intron | FLT3 | 46 | 0.107 | 0.000–0.124 | 9.15E-10 |
LUAD | 10413 | rs12591927 | 15 | 31833911 | intron | OTUD7A | 44 | 0.077 | 0.016–0.289 | 2.44E-08 |
LUAD | 10413 | rs17003208 | 22 | 43073031 | Intergenic | - | 45 | 0.074 | 0.096–0.431 | 1.13E-08 |
LUAD | 10413 | rs17003212 | 22 | 43079754 | Intergenic | - | 46 | 0.063 | 0.096–0.434 | 1.18E-11 |
LUAD | 12146 | rs4741498 | 9 | 15424938 | intron | SNAPC3 | 45 | 0.063 | 0.005–0.256 | 3.68E-08 |
LUAD | 12146 | rs7026970 | 9 | 15445219 | intron | SNAPC3 | 45 | 0.063 | 0.040–0.355 | 3.68E-08 |
LUAD | 12146 | rs7046713 | 9 | 15458921 | intron | SNAPC3 | 45 | 0.063 | 0.031–0.357 | 3.68E-08 |
LUAD | 14734 | rs341737 | 8 | 2782370 | Intergenic | - | 54 | 0.107 | 0.081–0.225 | 9.86E-09 |
PRAD | 10413 | rs7631369 | 3 | 1028679 | Intergenic | - | 48 | 0.070 | 0.015–0.418 | 3.45E-08 |
PRAD | 10413 | rs7301597 | 12 | 30175147 | Intergenic | - | 48 | 0.050 | 0.000–0.105 | 3.85E-09 |
THCA | 585 | rs17033484 | 4 | 156686737 | intron | GUCY1B3 | 54 | 0.089 | 0.058–0.187 | 3.78E-08 |
THCA | 4271 | rs2145836 | 20 | 47421064 | intron | PREX1 | 44 | 0.054 | 0.000–0.058 | 4.41E-08 |