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Fig. 3 | Genome Medicine

Fig. 3

From: Interrogating the “unsequenceable” genomic trinucleotide repeat disorders by long-read sequencing

Fig. 3

Performance of RepeatHMM, RepeatCCS, BAMself, and TRhist on estimating the repeat counts in ATXN3 for 20 patients with SCA3 and five controls. The gold standards (x-axis) were determined by capillary electrophoresis for 20 patients or by Sanger sequencing for five controls. a Scatterplot of estimated repeat counts and true counts. b, c The difference of estimated repeat counts and true counts by RepeatHMM, RepeatCCS, BAMself, and TRhist. RepeatCCS refers to the use of RepeatHMM on error-corrected reads generated by the circular consensus sequencing protocol

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