Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa

Table 1 Summary of key epidemiological features of ST313 sampled by PHE. Full metadata for all isolates in this study is available in Additional file 2: Table S2

A. Association between isolation source and travel to sSA. Total = 48^a
	Extra-intestinal infection	Gastro-intestinal infection
Reported travel to sSA	6	2
No reported travel to sSA	2	38
	OR = 57.0 (95% CI = 6.7–484.8), p value = 0.0002
B. Association between lineage 2 infection and travel to sSA. Total = 51^b
	Lineage 2	Non-lineage 2
Reported travel to sSA	7	1
No reported travel to sSA	2	41
	OR = 143.5 (95% CI = 11.4–1802.9), p value = 0.0001
C. Association between lineage 2 infection and extra-intestinal infection. Total = 72^c
	Lineage 2	Non-lineage 2
Extra-intestinal infection	10	3
Gastro-intestinal infection	1	57
	OR = 190.0 (95% CI = 17.9–2014.0), p value < 0.0001

^a51 individual patient isolates with travel information, but three with source unknown
^b51 individual patient isolates with travel information
^c75 individual human patient isolates in total, but three with source unknown. One isolate not included in phylogeny due to poor quality sequence, so lineage unknown

ISSN: 1756-994X