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Table 3 Mayo Clinic Brain RNAseq data for SAR1A and RAB10 genes in AD vs. control brains

From: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience

Gene ID Chr Start Stop Coding length Tissue Model Comparison Dx.Beta EffectDirection Dx.SE Dx.pValue Dx.qValue
RAB10 chr2 26256976 26360323 3631 TCX Compre Control_vs_AD 0.14 UpInAD 0.04 1.55E-03 7.12E-02
RAB10 chr2 26256976 26360323 3631 TCX Simple Control_vs_AD 0.32 UpInAD 0.05 6.96E-09 1.50E-06
SAR1A chr10 71907045 71930279 6914 TCX Compre Control_vs_AD -0.12 DownInAD 0.05 1.27E-02 1.80E-01
SAR1A chr10 71907045 71930279 6914 TCX Simple Control_vs_AD -0.10 DownInAD 0.04 2.07E-02 5.12E-02
  1. Gene ID, ENSEMBL gene ID; Tissue, TCX temporal cortex; Dx.Beta, coefficient of effect in AD in comparison to controls; Dx.SE, standard error of effect; Dx.pValue, significance of effect (uncorrected); Dx.qValue, significance corrected using FDR-based q-values