Fig. 1

Yield of clinically reportable CNVs in schizophrenia by IQ group. The figure depicts the percentage of individuals with schizophrenia for each of the IQ groups with one or more pathogenic (defined as pathogenic or VUS-likely pathogenic) CNV (a) or one or more CNV classified as a VUS (b), determined using the ACMG guidelines for CNV interpretation [28]. Individuals with more than one clinically reportable CNV were only counted once. Schizophrenia participants were assigned to each of the IQ sub-groups using the methods described in the manuscript. Average average, IQ intelligence quotient, BL borderline intellectual functioning, ID intellectual disability, NVLD non-verbal learning disability, VUS variant of unknown significance. Asterisks above horizontal brackets represent the significance of the between-group comparisons: *p < 0.05, **p < 0.01, ***p < 0.001, NS = p > 0.1. All other comparisons were non-significant