Fig. 6
From: Granatum: a graphical single-cell RNA-Seq analysis pipeline for genomics scientists
Protein–protein interaction network and pseudo-time construction steps. a The PPI network derived from the DE results between PDX primary and metastasized cells in the K-dataset. The color on each node (gene) indicates its Z-score in the differential expression test. Red and blue indicate up- and down-regulation in metastasized cells, respectively. b The pseudo-time construction step. The Monocle algorithm is customized to visualize the paths among individual cells. Sample labels from the metadata are shown as different colors in the plot