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Fig. 4 | Genome Medicine

Fig. 4

From: An integrative functional genomics framework for effective identification of novel regulatory variants in genome–phenome studies

Fig. 4

Illustration of tissue-specific TF-promoter/enhancer-target gene interaction network analysis. a Overview of the perturbed tissue-specific TF-target gene network in mental disorders. Blue links represent enhancer-perturbed TF-target gene interactions. Green links represent promoter-perturbed TF-target gene interactions. Several disease-associated genes are highlighted in the outside of the circle. b Enrichment analysis of the disease genes in the perturbed tissue-specific TF-target gene network

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