Skip to main content
Fig. 3 | Genome Medicine

Fig. 3

From: BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data

Fig. 3

De novo reconstruction of sc-RNA-seq data yields a single dominant transcript model for IgH and IgL. The number of sequencing reads mapping to the reconstructed Ig transcript models (IG_mapped+Unmapped method) using bowtie2 quantification are shown for 176 flu vaccine-induced human plasmablasts (AW2-AW3 dataset). a IgH transcript models using Unfiltered reconstruction. b IgL models from Unfiltered reconstruction. c Ratio of reads mapping to the top and second-most abundant transcript models from Unfiltered reconstruction for IgH and IgL. The dashed line indicates a twofold ratio between the top and runner-up models. Red lines represent medians of each dataset

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us