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Fig. 3 | Genome Medicine

Fig. 3

From: Sensitivity to sequencing depth in single-cell cancer genomics

Fig. 3

COSMIC and non-synonymous somatic SNV recall in single cells. a Barplots indicate the proportion of bulk COSMIC somatic variants detected in the single-cell datasets (COSMIC recall). Error bars indicate 95% confidence intervals. Numbers above bars indicate number of variants called. b Presence–absence profile of COSMIC SNVs across cells for replicate 1 of the W55 dataset. Colors illustrate mutation status: mutated allele, green; reference allele, grey; missing data, white. c Barplots indicate the proportion of bulk non-synonymous somatic variants detected in the single-cell datasets (non-synonymous recall). d Presence–absence profile of non-synonymous SNVs across cells for replicate 1 of the W55 dataset. Colors illustrate mutation status: mutated allele, green; reference allele, grey; missing data, white

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