Fig. 5
From: Enabling multiplexed testing of pooled donor cells through whole-genome sequencing
Estimating individual donor proportion of 102 PGP donors in a mixed pool. Individuals from Pool 0 are absent from the mixed pool while individuals from Pools 1, 2, 3, 4, and 5 are represented on average at 1X, 2X, 3X, 4X, and 5X, respectively (see “Methods”). a The estimated proportion (y-axis) at each iteration (x-axis) when running the algorithm. The different colors represent donors from different pools. b Box plot of the final estimate of the donor proportion for each pool. The blue dots indicate the estimate for each individual donor