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Table 1 Minimal read-depth required for accurate prediction of donor proportion

From: Enabling multiplexed testing of pooled donor cells through whole-genome sequencing

  500,000 SNPs 1,000,000 SNPs
100 donors 1X 1X
500 donors 30X 10X
1000 donors >30X 30X
  1. The read-depth necessary to obtain an accurate prediction of donor proportion with Pearson correlation coefficient > 0.9 for a mix pool of 100, 500, and 1000 unique donors when 500,000 and 1,000,000 SNPs are analyzed with our method