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Table 1 Minimal read-depth required for accurate prediction of donor proportion

From: Enabling multiplexed testing of pooled donor cells through whole-genome sequencing

 

500,000 SNPs

1,000,000 SNPs

100 donors

1X

1X

500 donors

30X

10X

1000 donors

>30X

30X

  1. The read-depth necessary to obtain an accurate prediction of donor proportion with Pearson correlation coefficient > 0.9 for a mix pool of 100, 500, and 1000 unique donors when 500,000 and 1,000,000 SNPs are analyzed with our method
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Genome Medicine

ISSN: 1756-994X

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