Fig. 8

CoGAPS gene signatures confirmed in independent in vitro and in vivo expression data. a–c Box plots of sample weights for HNSCC cetuximab sensitive cell lines SCC25, SCC1, and resistant 1CC8 in CoGAPS expression signatures. d–f Box plots of sample weights for HNSCC cetuximab-sensitive cell lines SCC25, SCC1, and resistant 1CC8 in CoGAPS methylation signatures. g-i Box plots of tumor gene expression profiles from relapsed HNSCC patients projected into CoGAPS expression signatures. Patient samples are stratified by length of progression-free survival